Capsule Sinkers

 

Floating dosage forms rarely dissolve at a reproducible rate. Using a sinker in Apparatus 2 fixes the dosage form to a certain point and aids reproducibility. Sinkers can also be useful where dosage forms may stick to the sides of the vessel.

General guidelines to consider when choosing a sinker for your application include: 

• Sinker Size - the sinker should have minimal surface contact with the tablet as this can affect the dissolution rate.

• Sinker Weight - should be kept to a minimum - just enough to have a desired effect.

• PTFE Coated Sinkers Magnetic - used with magnetic retrieval systems,  or where there may be a reaction between steel and the tablet.

• Uncoated - type 316 stainless steel sinkers are more durable than coated sinkers.

• Basket Sinkers - can be used but care should be taken that the outer coating of the tablet does not clog the mesh

• Wire Spirals - should be as wide as practically possible to avoid clogging.

 

 

 

Product Description	Image	Product Code
Japanese Pharmacopeia Basket Sinker		CERTBSK-JP
5.5 Spiral Stainless Steel Capsule Sinker 22.4 x 11.81mm Capacity.		CAPWHT-XLSS
4 Spiral Stainless Steel Capsule Sinker 33.5 x 11.7mm Capacity		CAPWHT-XLS
Felodipine Test Suspended Basket		STABSK-VK8
10 Spiral Stainless Steel Capsule Sinker 31.0 x 11.0mm Capacity		CAPWST-31
7 Spiral Stainless Steel Capsule Sinker 23.0 x 8.0mm Capacity		CAPWST-23
6 Spiral Stainless Steel Capsule Sinker 19.3 x 7.0mm Capacity		CAPWST-19
5 Spiral Stainless Steel Capsule Sinker 18.0 x 6.0mm Capacity		CAPWST-18
4 Spiral Stainless Steel Capsule Sinker 15.5 x 5.0mm Capacity		CAPWST-15
6 Spiral Stainless Steel Capsule Sinker 25.4 x 14.6mm Capacity		CAPWHT-XS
4 Spiral PTFE Coated Capsule Sinker 33.5 x 11.7mm Capacity		CAPWHT-XL
4 Spiral PTFE Coated Capsule Sinker 33.5 x 10.4mm Capacity		CAPWHT-LG
4 Spiral Stainless Steel Capsule Sinker 26.0 x 9.7mm Capacity		CAPWHT-4S
4 Spiral PTFE Coated Capsule Sinker 26.0 x 9.7mm Capacity		CAPWHT-04
6 Spiral Stainless Steel Capsule Sinker 22.9 x 9.4mm Capacity		CAPWHT-2S
6 Spiral PTFE Coated Capsule Sinker 22.9 x 9.4mm Capacity		CAPWHT-02
3 Pronged Capsule Sinker with Magnetic Top VanKel (Varian) Style		MAGWHT-VKTOP
3 Pronged Capsule Sinker, Uncoated Stainless Steel Vankel (Varian) Style		CAPWHT-SV
3 Pronged Capsule Sinker with Magnetic Legs VanKel (Varian) Style		MAGWHT-VK
3 Pronged Capsule Sinker VanKel (Varian) Style		CAPWHT-VK
O-Ring Sinker 316 stainless steel 11.8 x 25.8mm capacity		CAPWHT-S99
Time Release Capsule Sinker		CAPWHT-TR
Breath Film Sinker		CAPWHT-PC
40 Mesh Basket Sinker VanKel (Varian) Style		SNK040-VK
10 Mesh Basket Sinker VanKel (Varian) Style		SNK010-VK
8 Mesh Basket Sinker VanKel (Varian) Style		SNK008-VK
8 Mesh Basket Sinker Japanese Pharmacopeia Size		BSK008-JP
8 Mesh Basket Sinker		BSK008-01
Type 316 Stainless Steel Wire 0.6mm dia 15m Roll		WIRESK-VK